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User experiences vary dramatically with some reporting maintained benefits months after stopping while others notice gradual decline toward pre-treatment baseline, creating confusion about optimal usage patterns including continuous application versus cycling protocols
Moize V, Deulofeu R, Torres F, et al
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Patients with pancreatic insufficiency may have reduced cobalamin absorption (because pancreatic enzymes normally assist with the displacement of salivary haptocorrin binding protein by intrinsic factor), although such patients rarely become cobalamin deficient
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