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Pregnancy is an absolute contraindication at any dose
TSC2 forms a heterodimeric complex with TSC1 that suppresses the mTOR complex 1 (mTORC1) activity by inhibiting the small GTPase Rheb, an essential mTORC1 activator [263]
Units are 0.08 ml 100, which is 8 units
This is a theoretical risk not yet documented in KLOW-specific literature, but it's mechanistically plausible enough to warrant immediate investigation if symptoms appear
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