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However, when taken in excessive amounts, this effect can be amplified, leading to significant gastrointestinal distress
Adverse side effects are one of the leading reasons individuals discontinue therapy or are unable to increase their dose, even if they havent yet reached their desired goals
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Additionally, GLP-1 receptor agonists slow gastric emptying, which prolongs the feeling of fullness after eating, and they act on appetite centres in the hypothalamus to reduce hunger and food intake