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While postbiotics are unlikely to replicate the magnitude of weight loss achieved with GLP-1RAs, their continuous, physiology-aligned mode of action positions them as biologically plausible adjuncts that may support weight-loss sustainability and improve the metabolic context for lean mass preservation

The researchers found that berberine modestly lowered fasting glucose and hemoglobin A1C (HbA1C or A1C), two metrics used to assess blood sugar

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