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Additionally, dehydration which can occur secondary to the gastrointestinal side effects of GLP-1-based therapies, such as nausea and vomiting may compound the chronotropic effect by triggering a compensatory reflex tachycardia

In metabolic dysfunction-related steatohepatitis (MASH), preclinical models show GLP-1s reduced hepatic inflammation, lipid accumulation, and fibrosis-related markers

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Effects of L-carnitine on the hypoxic atria from fed and fasted rats