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It is a vital neurotransmitter and paracrine signaling substance that is mostly produced and released by intestinal enterochromaffin (EC) cells (251)
The review also delves into an examination of various nutritional antioxidants, namely vitamin C, vitamin E, carotenoids, selenium, zinc, polyphenols, coenzyme Q10, and probiotics, and elucidates their role in mitigating the adverse effects of oxidative stress arising from imbalances in adrenal hormone levels
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Clinical trials reached phase II before the program was discontinued
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