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The study found that while glutathione was elevated, other vital protective antioxidant enzymessuch as mitochondrial superoxide dismutase (SOD2)were severely depleted

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Specifically, the skin contains all the components required for local estrogen synthesis, including 17-hydroxysteroid dehydrogenase (17-HSD), 3-hydroxysteroid dehydrogenase (3-HSD), aromatase and 5-reductase [4851]

No negative interaction [26]