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There is a wealth of data identifying DPP-4 as a receptor or ligand for a variety of different molecules which, either alone or in combination with its enzymatic activity, allow it affect physiological processes such as the interaction between cells and the extracellular matrix, cell migration, and proliferation
Intracellular Glu is produced from glutamine (Gln) catalyzed by glutaminase (GLS, with two different isomers GLS1 and GLS2) [29, 30]
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