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Among the main inflammatory mediators, CRP plays a crucial role in atherogenesis by promoting complement activation, enhancing macrophage lipid uptake, stimulating pro-inflammatory cytokine release, inducing monocyte tissue factor expression, impairing endothelial function, and inhibiting nitric oxide production, further aggravating vascular injury (Shrivastava et al

For example, in mature plant cells, the vacuole typically occupies nearly 90% of the cell volume 54 , leaving limited space for other organelles to move freely and transport rapidly, particularly for large or tubular organelles