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We find that haploinsufficiency for SLC25A51 lowers mitochondrial NAD + and impairs regeneration despite unchanged whole-tissue NAD + levels and, conversely, that overexpression of SLC25A51 raises mitochondrial NAD + content and improves regeneration comparably with the effect of systemic NAD + precursor supplementation
Signs of dehydration: Symptoms such as dizziness, decreased urination, dark urine, rapid heartbeat, or confusion may indicate significant dehydration requiring medical intervention, particularly if gastrointestinal side effects are severe
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