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Diagnosis usually occurs incidentally through imaging studies such as ultrasound or via risk-based case finding
In Functional Medicine, its used as a powerful supplement to support heart health, reduce inflammation, and promote healthy aging
Focus on progressive overload where possible
found the exendin-4 Trp-cage does not directly interact with the GLP-1R ECD (Runge et al., 2008), although analysis of photo-crosslinking data using the full length receptor showed that the flexible exendin-4 C-terminus might snake over the top of the ECD and form interactions with Phe80, Tyr101 and Phe103 (Koole et al., 2017)
The high fat content in KD lowers the oesophageal sphincter tone, slows gastric emptying, and decreases intestinal transit time
