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GLP-1s were first used for treating type 2 diabetes
In the Goto-Kakizaki (GK) rat, a spontaneous model of T2DM [51], intravitreal E4 prevented cell loss in the GCL and outer nuclear layer (ONL) without affecting systemic glucose levels, suggesting a local retinal mechanism
The best absorption typically occurs when tablets are taken on an empty stomach, approximately 30-60 minutes before meals or 2-3 hours after eating
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