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Sodiumglucose co-transporter 2 (SGLT2) inhibitors, the most recently developed oral hypoglycemic agents acted on renal proximal tubules, suppress glucose reabsorption and increase urinary glucose excretion
& Alter, B
"Insulin resistance and endothelial function are improved after folate and vitamin B12 therapy in patients with metabolic syndrome: relationship between homocysteine levels and hyperinsulinemia"
A recent systematic review of GLP-1 agonist exposure found that animal studies showed risks such as fetal growth restriction and skeletal abnormalities, and due to limited human data, experts recommend stopping these medications in both pregnancy and during breastfeeding
If one needs a higher level of pain medications, then one should see a physician for assessment as to whether there are other concurrent injuries or if one does need different medications to treat their injury
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