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The enriched GSH transporters in the blood brain barrier has been effectively employed for the design of brain targeting prodrugs and brain drug delivery systems

doi:10.1002/jcp.25693 [PubMed] Narvaez J, Maldonado G, Intriago M, et al

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In particular, whether pharmacological recovery of GLP-1R metabolic function or functional connectivity also restores the other is an interesting question both for medical imaging biomarkers and the development of such drugs