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The immunogenicity findings have important practical implications
(Diabetes Obes Metab 2024) found no clinically relevant QTc prolongation
This metabolic shift elevates cytosolic lactate concentrations from physiological levels (1.53 mM) to pathological levels (1030 mM) in cancer cells
While I agree that it is misunderstood as a weaker and therefore safer alternative to opioid and that you do see a lot of tramadol misuse and abuse because of this sentiment, I still stand by its use instead of oxycodone/acetaminophen or hydrocodone/acetaminophen
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