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However, the review did not find a consistent, proven direct effect on libido outside of the influence on weight and hormones For healthy men: a study with 18 healthy men in the UK suggests that GLP-1 does not appear to directly affect sex drive or reproductive hormones in healthy men

The ongoing integration of genomics, transcriptomics, proteomics, metabolomics, and other omics technologies promises to refine GLP-1 based T2DM strategies through detailed characterization of L cell subtypes and gene regulatory networks etc (22, 23)

In the same study, there were no differences between diet groups in free testosterone, androstanediol glucuronide or luteinizing hormone

Latif W, Lambrinos KJ, Patel P, Rodriguez R

This differs from the sometimes flat affect associated with certain psychiatric medications