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What to monitor: Weight, blood pressure, heart rate (especially with phentermine) Compliance and tolerance Mental health status (mood, suicidality screeningeven though GLP-1s dont increase risk, its good practice) Labs periodically (glucose, kidney function if on GLP-1s long-term) PDMP Checks (Controlled Substances) If prescribing phentermine or other controlled substances, most states require checking the Prescription Drug Monitoring Program before each prescription: Mandatory in: Florida (E-FORCSE), Texas, New York (I-STOP), Illinois, California, Pennsylvania, and most others
Endocrine/Metabolic Dec
Dose adjustment, protocol modification, or reevaluation of injury severity and type may be appropriate
Retatrutides side effect profile is still being studied, although available trial data suggests digestive symptoms are common and can be dose-related
Reduction of prevalence of patients meeting the criteria for metabolic syndrome with tirzepatide: a post hoc analysis from the SURPASS Clinical Trial Program
