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The concept of long-term stores is a simplification that overlooks the rapid metabolic turnover and the fact that a symptomatic patient may experience a swift decline in their well-being as the effects of the last injection wane
In addition to KEAP1, which is the main negative regulator of NRF2 protein stability, many other factors which negatively regulate NRF2 have been discovered and characterized
Serious risks could happen, too
Pearce et al
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