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(2016), publie dans Obesity Reviews

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The SURPASS-1 trial demonstrated significant improvements in glycemic control and substantial reductions in body weight with all three doses of tirzepatide (5 mg, 10 mg, or 15 mg) compared to placebo over a 40-week period

Its use in non-clinical experimental designs supports investigations into mitochondrial function, lipid-associated signaling mechanisms, and cofactor-driven enzymatic activity, contributing to broader research into metabolic regulation and cellular bioenergetics

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