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DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids.[5] In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH)
Free copper ions generate reactive oxygen species through Fenton-like reactions
Moisturizes the skin from within and maintains its soft and supple texture
Can glutathione be combined with other treatments
They also found that curcuminoids enhanced the accumulation of mitoxantrone and pheophorbide in ABCG2-expressing MCF-7 AdVp3000 cells, in a concentration dependant way [240]
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