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Increased vascularization supports nutrient delivery and waste removal, which are important for oocyte quality and embryo implantation

Although these changes did not reach statistical significance, they were accompanied by a twofold decrease in plasma leptin levels, consistent with fat mass reduction

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Expected Timeline: The brightening process can be visible as early as 3 days after the first injection

Males and females were treated with 20 mM BSO (19176, Sigma-Aldrich) in the drinking water starting at 21 days of age, immediately after weaning