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However, our rigorous matching procedures with the intention to achieve a greater level of between-group comparability on a wide range of baseline patient characteristics (i.e., prior GLA exposure history, comorbidities, diabetes severity, and co-medications) and the regression analyses with adjustment for imbalanced baseline characteristics may have minimized this concern

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In addition, regulatory and quality personnel are needed

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Klauda JB, Venable RM, Freites JA, OConnor JW, Tobias DJ, Mondragon-Ramirez C, Vorobyov I, Mackerell AD Jr, Pastor RW (2010) Update of the CHARMM all-atom additive force field for lipids: validation on six lipid types