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Obesity Increases Inflammation These two conditions feed off of each other, so addressing one alone is often not enough when you are dealing with a patient who has moderate to severe psoriasis, as well as obesity, says Bordone

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In practical terms, tirzepatide does three things: Slows how quickly food leaves your stomach, so you feel full longer Reduces appetite signals from the brain, so cravings drop Improves how your body uses insulin, which helps blood sugar control It's given as a weekly injection under the skin, starting at a low dose and stepping up over several weeks to a target of 5 mg, 10 mg, or 15 mg per week