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This is simply the inverse of a strategy used by some large DNA viruses to maximize DNA production, by encoding their own thioredoxin-like proteins, glutaredoxins and even entire RNR genes (22)

Frontiers in Aging Neuroscience, 14 , 888292

The immune cells in these patients are dealing with such an extreme, unrelenting burden of oxidative stress and mitochondrial lipid damage that they have frantically ramped up their own internal glutathione production in a desperate attempt to survive

10.3389/fncel.2022.841731 72 WangY.CaoP.AlshwmiM.JiangN.XiaoZ.JiangF.et al (2019)