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Glutathione injections offer fast absorption but require medical supervision

Acknowledgements We acknowledge the support of the staff of the Pennsylvania State University College of Medicine Clinical Research Center and Investigational Pharmacy

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By employing physical encapsulation or chemical conjugation, these platforms circumvent the physicochemical limitations inherent to many PROTACs, thereby liberating medicinal chemistry efforts from the empirical correction of poor drug-like properties and enabling a sharper focus on optimizing the ternary complex for maximal degradation activity [56, 276,277,278]

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