Once into the brain, Vit B12 interacts with genes (LRRK2), proteins (synuclein and Lewy bodies), neurotransmitters (dopamine, Acetylcholine (Ach)) and metabolites that do impact on CNS hemostasis
While some research suggests that B12 levels may influence fat metabolism and body composition, the relationship isnt fully understood
This crucial vitamin is the only one our bodies have a hard time absorbing and digesting directly from food sources
For many patients, their injections dont last long enough Some clinicians assume (incorrectly) that 1000 mcg of B12 should last patients at least 200 days, calculating from a 5 mcg daily requirement for the vitamin
It cannot establish human safety, correct counterion, effective exposure or clinical benefit