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Aging is a network problem
FIGURE 7 The strong role of severe oxidative stress, reduced antioxidant defenses like GSH with increased lipid peroxidation and malondialdehyde generation (213), lipid, protein and DNA oxidation with increased apoptosis and necrosis in atherosclerosis as a major cause of cardiovascular diseases and stroke, supports the use of complementary and alternative medicines, dietary supplements, and antioxidants with hardly any adverse effect, able to restore homeostasis reversing oxidative stress (214)
A major role for ferroptosis in Mycobacterium tuberculosis -induced cell death and tissue necrosis
Outcome measures included GSH levels in whole blood, erythrocytes, plasma, and lymphocytes, as well as exfoliated buccal mucosal cells
Overview of the GSH system The anabolic process and redox status of GSH in the myocardium under physiological conditions Synthesis of GSH The synthesis of glutathione is found in almost all mammalian cells [23]
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