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14 Over the past several years, there has been an emergence of cohort studies, clinical trials, systematic reviews, and meta-analyses examining the safety, efficacy, and clinical outcomes of GLP-1 receptor agonists in the treatment of AUD
Like the other incretins, Zepbound can cause side effects, such as nausea, burping, diarrhea, vomiting, constipation, stomach discomfort and pain, injection site reactions, fatigue, fever, rash, hair loss and gastroesophageal reflux disease
The safety and efficacy of coadministration with other products for weight management have not been established
Recently, a high-resolution crystal structure of phosphinic pseudopeptide inhibitor 45 (DG046) in the closed-conformation of ERAP1 was disclosed (Giastas et al., 2019b) and a mechanism for antigen peptide selection by ERAP1 presented (Giastas et al., 2019a)
2002;99(15):9745-9749.[DOI] 13
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