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For patients with type 2 diabetes, a 26-week phase II trial showed that 48% of participants achieved at least 10% weight reduction after treatment with orforglipron 45 mg

The vagus nerve connecting the hypothalamus to the gastrointestinal tract relays messages regarding gastrointestinal distension and gut hormones

doi: 10.3390/nu13041317 76 Trius-SolerMMorenoJJ

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