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In addition, in the vast majority of these studies, liraglutide was used at low or medium doses, while it is well known that some effects, in particular weight loss, are dose-dependent and more pronounced at the maximum dose

Genetic factors influence individual responses to GLP-1 therapy and kidney resilience

In the insulin glargine group, the insulin dose was titrated according to the treatment standard algorithm, with the goal of fasting blood glucose lower than 100 mg/dL

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Investigators concluded that ROSE-010 reduced IBS pain but caused nausea, vomiting, and headaches, necessitating careful monitoring and personalized treatment