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[2] The Phase 3a REDEFINE 2 trial then tested once-weekly CagriSema (cagrilintide 2.4 mg plus semaglutide 2.4 mg) against placebo in 1,206 adults with obesity and type 2 diabetes over 68 weeks, reporting a mean bodyweight change of 13.7% versus 3.4% for placebo

Consider using waist circumference measurements (taken at the navel level, first thing in the morning), progress photos taken under consistent lighting every 2 to 4 weeks, and DEXA scans every 3 to 6 months for the most accurate body composition data

For many others, high-dose oral B12 works just as well (NIH ODS

Side effects stated that are due to immunotherapy (2) diarrhoea - colitis rash auto-immune endocrine disturbance e.g