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Furthermore, our previous animal experiment demonstrated that glutathione enhances mitochondrial biogenesis by increasing peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1), 4 which is increased by exercise and enhances mitochondrial biogenesis

doi: 10.3390/antiox11010172 121

Diet quality as assessed by the healthy eating index, alternate healthy eating index, dietary approaches to stop hypertension score, and health outcomes: an updated systematic review and meta-analysis of cohort studies

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The practical rule that follows directly from this chemistry is to apply vitamin C in the morning (where UV exposure and its antioxidant role are relevant) and apply the copper peptide serum at night