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Daver N, Kantarjian H, Garcia-Manero G, Jabbour E, Borthakur G, Pierce S, Vaughan K, Ning J, Gonzalez G, Pemmarjau N, Kadia T, Konopleva M, Andreeff M , DiNardo C, Cortes JE, Craig A, Ravandi F

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IGF-1 Des is a naturally occurring analog of insulin-like growth factor 1 (IGF-1) found in the human brain and pig uterine tissues

Patients should not use the capsules beyond this date, as potency could diminish or the formulation could potentially become less stable

Every-other-weekly administration of BIO89-100 did not improve markers of glycemic control, with only the highest once-weekly dose showing a trend towards improvements (299)