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In the comprehensive preclinical studies, MDR-001 has demonstrated excellent functional potency and selectivity, with favorable ADME properties and oral bioavailability, as well as desirable pharmacokinetics and tolerability

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N Engl J Med 381:841851 McGuire DK, Marx N, Mulvagh SL et al (2025) Oral semaglutide and cardiovascular outcomes in High-Risk type 2 diabetes

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On the contrary, the positive effect of GIP on glucagon secretion is preserved [34]

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