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For comfort, some patients prefer to let the pen reach room temperature before injection by removing it from the refrigerator 30 to 45 minutes before use

Use whichever standard allows you to maintain adequate rotation across your available injection area

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A recent paper published in Rheumatology reported six female patients who developed herpes zoster infections within 3 to 14 days of receiving either the first or second dose of the Pfizer-BioNTech mRNA Covid-19 vaccine

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