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Nasal Sprays and Patches Non-invasive alternatives, with effects developing over several days to a week

Understand Their Decision: If they defer you, ask for clarification

In one trial of people with obesity and knee osteoarthritis, top-line results released in late 2025 showed that those receiving 12 mg weekly achieved 2226% average weight loss over 68 weeks , while the placebo group lost only around 2.5%

Semaglutide is usually administered once a week via injection, and its long-acting nature ensures a steady state of medication in your body, providing a continuous effect on blood sugar levels

However, the researchers noted that more studies are needed to confirm the results