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In brief, the amine-functionalized polyethylene glycol (PEG), alendronate (Ald), and ethyl L-methionine (Met) were sequentially coupled with the carboxyl group of HA through amination, followed by electrostatic and hydrophobic interactions to self-assemble with Sin, forming the PAM-HA@Sin NPs
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A safety survey 3 of intranasal glutathione highlighted the mild side effects, including irritation of nasal passages and headaches
Biochemical characteristics Peptide Sequence: Gly-His-Lys (Cu 2+ ) Molecular Class: Copper-complexed Tripeptide Metal Coordination: Cu 2+ bound to histidine and amine residues GHK exhibits strong affinity for copper ions, and metal coordination supports distinct biochemical behaviors compared to the uncomplexed tripeptide
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