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Additionally, MMP-2 is frequently implicated in cardiac pathologies (69), a common outcome in those diagnosed with PTSD (70)
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Myostatin normally binds ActRIIB ALK4/5 co-receptor recruitment SMAD2/3 phosphorylation SMAD4 complex nuclear translocation transcriptional upregulation of Atrogin-1/MAFbx (E3 ubiquitin ligase) and MuRF1, driving protein degradation and satellite cell quiescence
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