Furthermore, there was no significant difference in cellular recycling between Tanzeum and GLP-1 WT, while the effect of L585 truncation was apparent, with 2-fold less of GLP-1 LX being recycled compared to the WT counterpart (Fig
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doi: 10.1111/apt.2013.37.issue-11 26 LiuNAndoTIshiguroKMaedaOWatanabeOFunasakaKet al
One thing to watch out for is timing
Lancet Diabetes Endocrinol 5(5):355366 Lingvay I, Catarig AM, Frias JP, Kumar H, Lausvig NL, le Roux CW, Thielke D, Viljoen A, McCrimmon RJ (2019) Efficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial