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doi:10.1016/j.blre.2012.03.002 Eelderink C, Kremer D, Riphagen IJ, et al

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Because CJC-1295 acts upstream of growth hormone, its safety profile is tied to two overlapping issues: Peptide-specific effects , such as injection-site reactions or transient flushing GH/IGF-1-axis effects , such as fluid retention, joint discomfort, changes in glucose handling, or other effects associated with elevated growth hormone signaling The safety discussion is also complicated by naming

However, significant physical effects like increased muscle mass or fat loss might take several weeks of consistent use to become apparent

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