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The patient was 79 years old in April, when a request was made to get him the drug through the FDAs compassionate use pathway, which is typically reserved for patients with serious, life-threatening conditions who want to try experimental treatments

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And with so little definitive data on the long-term health effects of takingor stoppingthis new class of drugs, weight-loss companies suggestion that the drugs can be taken temporarily is worrying, says Ragen Chastain, a researcher, board-certified patient advocate, and author of a newsletter that explores weight science

Changes in energy levels can be variable

For example, a review in the Journal of Clinical and Aesthetic Dermatology found some benefit for skin brightening