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Nutrients 11 (10), 11
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Because type 2 diabetes increases fracture risk despite patients often having normal or high bone mineral density (BMD) theres growing concern about how these medications might influence bone health during GLP1 treatment
(13) Preclinical studies have demonstrated that GLP-1 receptor agonists like exenatide can enhance bone mass in diabetic and insulin-resistant rat models by upregulating OPG expression and improving the OPG/RANKL ratio
Joseph, Doug Lunsford, Eneida Mendonca, Marc P
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