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In individuals with confirmed B12 deficiency, correction may help normalise homocysteine metabolism, as deficiency has been associated with elevated homocysteine levels
It is supplied to the laboratory market as a research-use-only reference compound
PMCID: PMC3186286 Wright JW, Harding JW
It is synthesized endogenously in the liver and kidneys, and can also be obtained through dietary sources such as meat, fish and dairy products
For most patients, sustained cardiometabolic benefit will require long-term, continuous use, making one-time or short-term coverage insufficient
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