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Addressing Patient Expectations and Concerns Despite the promise of the GLP-1 Revolution , patient expectations need managing

Although findings from clinical studies are promising, there are concerns that long-term exposure of GLP-1 RAs at supratherapeutic or maximum approved maintenance doses may impair muscle cell differentiation and potentially contribute to the development of sarcopenia, despite their potential to improve muscle metabolism and quality [83, 88]

The edges of the phagophore bend and ultimately seal to generate a typically spherical, double-membraned autophagosome with a diameter of 300-900 nm, depending on the organisms and cargo types (6)

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However, because people on GLP1 medications usually eat less overall , nutritional adequacy matters more particularly during flu season when recovery demands are higher