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Mounjaro (tirzepatide) is a glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist licensed in the UK for the treatment of type 2 diabetes mellitus and, more recently, for weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
Given that progesterone plays such a significant role in PMDD, its not surprising that some treatments focus on modulating its levels
| FSA/HSA eligible: Yes Available in select states, Walgreens offers Ozempic, Wegovy, Zepbound and Saxenda as soon as the same day for eligible patients
Semaglutide The head-to-head trials (SURPASS-2 for T2D, SURMOUNT-5 for obesity) provide the clearest comparison
Cureus 2023;15:e46091
