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Lower doses worked, but not as much

Based on the available research, I believe conservative dosing produces the best outcomes for most people

Trends Mol Med 27:895906 Kovarik JJ, Bileck A, Hagn G, Meier-Menches SM, Frey T, Kaempf A, Hollenstein M, Shoumariyeh T, Skos L, Reiter B, Gerner MC, Spannbauer A, Hasimbegovic E, Schmidl D, Garhofer G, Gyongyosi M, Schmetterer KG, Gerner C (2023) A multi-omics based anti-inflammatory immune signature characterizes long Covid-19 syndrome

If you find injecting into your abdomen is less painful than in your arm, for example, you might find this location easier for injecting

Since obesity is a long-term condition, some people may need ongoing treatment