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These changes may explain why some people report pain or discomfort from things that normally wouldnt hurt, like clothing, bedsheets, or light touch
The 4mg dose maintained 70 to 85% of the weight lost at higher doses for many participants, representing a significant reduction in cost and side effect burden while preserving most of the results
Attributing skin changes solely to GLP-1 medication without considering these multiple variables would be an oversimplification
Corticosteroid injections: Effective for pain relief but associated with collagen fiber weakening and increased re-injury risk with repeated administration
The original STEP 1 trial randomized 1,961 adults with obesity to receive either semaglutide 2.4 mg or placebo for 68 weeks alongside lifestyle intervention
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