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Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
It remains under investigation in clinical trials registered on ClinicalTrials.gov and the EU Clinical Trials Register, and is not licensed for prescription or self-administration outside of formally approved research settings
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All the cell culture models can be used with a variety of cell types such as immortalized cell lines, primary cultured cells, and pluripotent stem cells
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