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From a public health perspective, the increase in healthcare expenses associated with MASLD and its complications is significant, underscoring the urgent need for effective treatment strategies that tackle both the liver-specific issues and the broader metabolic risks faced by affected individuals [2]
The dual mechanism appears to shift weight loss more towards fat mass specifically, which helps explain the difference in lean mass proportions between the two drugs in trial data
Indianapolis-based Eli Lilly manufactures the drugs Zepbound and Mounjaro, while Danish company Novo Nordisk makes Ozempic and Wegovy
Anecdotal evidence reported an improvement in energy levels
Some GLP-1 options have also demonstrated cardiovascular benefits, and newer incretin-based medications include dual-agonists (such as GIP/GLP-1) that work similarly but are not exactly the same drug class
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