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The authors conducted a two-year observational study that explored changes in body weight, cardiometabolic and endocrine parameters in obese women with PCOS who continued taking metformin after stopping semaglutide
It hasn't been well studied in pregnancy, so the cautious, honest answer is not to start it while pregnant or breastfeeding without a physician's guidance
10.1039/C5FO00007F 90
Both cause similar side effects, primarily gastrointestinal issues like nausea, diarrhea, and constipation
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